P7C3 suppresses astrocytic senescence to protect dopaminergic neurons: Implication in the mouse model of Parkinson’s disease

• DOI: 10.1111/cns.14819
• Publication Date: 2024-07-26T09:05:03Z
• Authors: Yajing Chen; Zengyan Zhu; Yinghui Yan; Hongyang Sun; Guanghui Wang; Xiaohuan Du; Fang Li; Shuwei Yuan; Wenjing Wang; Mei Wang; Chao Gu
• Keywords: Senescence

Astrocytic senescence is inextricably linked to aging and neurodegenerative disorders, including Parkinson's disease (PD). P7C3 a small, neuroprotective aminopropyl carbazole compound that exhibits anti-inflammatory properties. However, the effects of on astrocytic in PD remain be elucidated.