Anal function after endoluminal locoregional resection by transanal endoscopic microsurgery and radiotherapy for rectal cancer

• DOI: 10.1111/codi.13656
• Publication Date: 2017-03-17T11:02:38Z
• Authors: I. Biviano; A. Balla; D. Badiali; S. Quaresima; G. D'Ambrosio; E. Lezoche; E. Corazziari; A. M. Paganini
• Keywords: Anorectal manometry; Internal anal sphincter; Chemoradiotherapy; External anal sphincter; Anal sphincter

In patients with rectal cancer, surgery and chemoradiotherapy may affect anal sphincter function. Few studies have evaluated anorectal function after neoadjuvant (n-CRT) and/or transanal endoscopic microsurgery (TEM). The aim of this study was to evaluate the effects n-CRT TEM on function.Thirty-seven cancer underwent manometry Wexner scoring for faecal incontinence at baseline, (cT2-T3N0 cancer) 4 12 months surgery. Water-perfused measured tone rest during squeezing, sensitivity compliance. Twenty-seven 10 patients, respectively, without (Group A) or B).In Group A, resting pressure decreased from 68 ± 23 54 26 mmHg (P = 0.04) improved (60 30 mmHg). score showed a significant increase in gas (59%), soiling (44%) urgency (37%) rates months, followed by clinical improvement 1 year (41%, 26% 18%, respectively). group B, 65 50 18 but remained stable (44 11 mmHg, P 0.02 vs preoperative values - no difference compared evaluation months). Gas incontinence, were observed 50%, 25% 38%, 12% cases, treatment.TEM does not significantly Instead, causing major incontinence.