Postoperative outcomes and management strategies for coronary artery disease in patients in need of a lung transplantation

• DOI: 10.1111/ctr.13026
• Publication Date: 2017-06-28T16:41:00Z
• Authors: Sameer J. Khandhar; Andrew D. Althouse; Suresh Mulukutla; Robert Kormos; Catalin Toma; Oscar Marroquin; Elizabeth Volz; Leben Tefera; Christian Bermudez
• Keywords: Adult; Lung Diseases; Male; Databases, Factual; Coronary Artery Disease; Middle Aged; Survival Analysis; Perioperative Care; 3. Good health; 03 medical and health sciences; Logistic Models; Treatment Outcome; 0302 clinical medicine; Myocardial Revascularization; Prevalence; Humans; Female; Aged; Follow-Up Studies; Lung Transplantation

Abstract Background Patients requiring lung transplantation ( LT x) may also have coronary artery disease CAD ). The peri‐operative management and long‐term outcomes of these patients are not well established. Methods referred for x from 2008 to 2014 were included in this study. was defined by angiography as no (stenosis <20%), moderate (20%‐69%), significant ≥70%). Revascularization per recommendations local heart team. Postoperative cardiovascular survival reported. Results A total 1493 screened during period 656 received a transplant. Of the that underwent x, 51% had , 33% non‐obstructive 16% obstructive . Forty‐three revascularization. There increased risk events or adjusted mortality with HR =1.24, 95% CI : 0.83‐1.86, P =.290) including those Conclusions is high prevalence population advanced transplantation. Careful evaluation treatment can allow all severities revascularization successfully undergo x.