Postoperative acute kidney injury and renal replacement therapy after DCD lung transplantation

• DOI: 10.1111/ctr.14468
• Publication Date: 2021-08-21T20:21:05Z
• Authors: Alessandra Verzel...; Davorin Sef; Vladimir Trkulja; Binu Raj; Nicholas James Lees; Christopher Walker; Ian McGovern; Jerry Mitchell; Fabio De Robertis; Ulrich Stock
• Keywords: Renal replacement therapy

Acute kidney injury (AKI) after lung transplantation (LTx) is a common complication. We aimed to assess whether donation circulatory death (DCD) associated with an increased risk of AKI and renal replacement therapy (RRT) in the early postoperative period compared brain (DBD). Retrospective data on cohort (N = 95) LTx patients (DCD n 17, DBD 78) characterized by no use ex-vivo perfusion were analyzed for incidence within 30 days RRT 7 days. After optimal full matching, imbalance remained between DCD respect intraoperative cardiopulmonary bypass (CPB). Therefore, further subset (n 77) was defined that excluded CPB patients, matching repeated 13 vs. 63) resulting fair balance range preoperative characteristics ECMO. In both matched subsets, around twice higher conclusion, suggest could be worse outcomes justify studies topic order refine care pathways perioperatively.