Outcomes of dual kidney transplants from high KDPI kidneys are superior compared to single kidney high KDPI transplants at 1 year

• DOI: 10.1111/ctr.14737
• Publication Date: 2022-05-28T15:55:07Z
• Authors: Devika Das; Josiah Wagler; Stephanie Ohara; Michelle Nguyen; Peter E. Frasco; Maxwell Smith; Hasan Khamash; Amit K. Mathur; Pooja Budhiraja; Kunam Reddy; Raymond Heilman; Caroline Jadlowiec
• Keywords: Glomerulosclerosis

Dual kidney transplantation (DKT), utilizing two adult kidneys from the same donor for one recipient, has been used as a way to expand available pool. These often come high Kidney Donor Profile Index donors (KDPI > 85%). Data comparing outcomes between KDPI DKT and single transplants (SKT) remain limited. We assessed of 336 performed at our center; 11.0% (n = 37) were DKT. Recipients older (P .02) had higher score (median 96% vs. 91%, P < .0001). operative time was compared SKT (+1.4 hours, There no differences in delayed graft function (54.1% 51.5%, .77) hospital length stay 4.0 3.0 days, .21) SKT. Grade I Clavien-Dindo complications occurred 8.1% 13.7% .008). grade IVa, IVb, or V either group. more glomerulosclerosis .04), interstitial fibrosis .02), tubular atrophy .01), arterial thickening .03) on 1-year protocol biopsies. Estimated glomerular filtration 1- .004) 2-years post-transplant .01). patient (HR 1.3, 95% CI .5-3.3, .58) 1.1, .5-2.3, .83) survival. Good can be achieved with using moderate chronic changes. is good option help further utilize minimize discard.