Second Time Around: Increased Rate of Living Donation From Repeat Organ Donors

• DOI: 10.1111/ctr.70049
• Publication Date: 2025-01-06T19:29:49Z
• Authors: Carolyn N. Sidoti; Kelly Terlizzi; Conor Donnelly; Ian S. Jaffe; Jennifer D. Motter; Benjamin Philosophe; Reed T. Jenkins; Sarah Hussain; Pedro Colon; Amit D. Tevar; Bonnie E. Lonze; Babak J. Orandi; Macey L. Levan; Dorry L. Segev; Allan B. Massie

ABSTRACT Introduction Some living organ donors will decide to donate again at a later date. Evidence has indicated that this practice may have increased in recent years. We evaluated the incidence and outcomes of inform counseling potential repeat donors. Methods Using SRTR data from 1994 2023, we identified 220 their 415 recipients. constructed donor comparison groups using weighting by odds. described clinical lab results 6 months, 1 year, 2 years post‐donation separately for kidney‐second liver‐second compared all‐cause graft failure recipients with those Results The annual count 5 2018 25 2019 ( p < 0.001). Of donors, 159 were (72.3%) 55 (25.0). percentage nondirected donations 30.5% first donation 53.2% second Liver‐second had one death approximately 2.5 post‐donation. Seventeen re‐admitted 20 experienced complications requiring an interventional procedure or re‐operation. Among no deaths, re‐admissions, reported. Post‐donation both comparable when against organ‐specific Recipients survival similar Conclusions Repeat be safe carefully selected short term; however, long term safety is unknown. Outcomes are