Multicenter prospective evaluation study of endoscopic ultrasound‐guided hepaticogastrostomy combined with antegrade stenting (with video)

• DOI: 10.1111/den.12976
• Publication Date: 2017-10-21T01:56:41Z
• Authors: Takeshi Ogura; Masayuki Kitano; Mamoru Takenaka; Atsushi Okuda; Kosuke Minaga; Kentaro Yamao; Yukitaka Yamashita; Keiichi Hatamaru; Chishio Noguchi; Yasuhiko Gotoh; Taira Kuroda; Tomoyuki Yokota; Hidefumi Nishikiori; Ryota Sagami; Kazuhide Higuchi; Yasutaka Chiba
• Keywords: Clinical endpoint; Endoscopic Ultrasound; Hyperamylasemia

Background and Aim Endoscopic ultrasonography‐guided hepaticogastrostomy ( EUS ‐ HGS ) is often indicated for advanced stage patients. Therefore it important to prevent adverse events associated with procedures obtain long stent patency. ‐guided antegrade stenting AS has been developed as an technique. Thus, achieve patency, combined HGAS reported. The aim of the present study was evaluate technical feasibility efficacy in a multicenter, prospective study. Methods This carried out at each hospital Therapeutic Ultrasound Group. Primary endpoint this multicenter patency . Results A total 49 patients were enrolled. Technical success rate 95.9% (47/49). failed five because guidewire could not be into intestine across bile duct obstruction site. Therefore, successfully 40 (technical rate: 85.7%). Median overall survival 114 days. including dysfunction patient death In contrast, mean 320 Adverse seen 10.2% (5/49) cases. Hyperamylasemia four patients, bleeding one patient. Conclusions first clinical benefit obtaining avoiding events, although possibility acute pancreatitis result orifice pancreatic must considered.