Safety and efficacy of the endoscopic delivery of capsule endoscopes in adult and pediatric patients: Multicenter Japanese study (AdvanCE‐J study)

• DOI: 10.1111/den.14104
• Publication Date: 2021-08-11T18:30:18Z
• Authors: Naoki Ohmiya; Shiro Oka; Yoshiko Nakayama; Itaru Iwama; Masanao Nakamura; Hirotaka Shimizu; Akihiko Sumioka; Naoki Abe; Takahiro Kudo; Satoshi Osawa; Hitoshi Honma; Takeru Okuhira; Shoji Mtsufuji; Hiroyuki Imaeda; Kazuhiro Ota; Ryo Matsuoka; Naoki Hotta; Mikihiro Inoue; Konosuke Nakaji; Hiroyuki Takamaru; Keiji Ozeki; Taku Kobayashi; Naoki Hosoe; Hisao Tajiri; Shinji Tanaka
• Keywords: Capsule; Enteroscopy; Gastroparesis; Transverse colon; Jejunum

We retrospectively determined the safety and efficacy of endoscopic delivery (ED) capsule endoscopes.We enrolled 10,156 patients who underwent small bowel endoscopy (SBCE), 3182 patency (PC), 1367 colon (CCE), at 11 gastroenterological nine pediatric centers.Small endoscopies, PCs, CCEs were endoscopically delivered to 546 (5.4%), 214 (6.7%), 14 (1.0%) patients, respectively. Only mild complications occurred for 21.6% (167/774), including uneventful mucosal damage, bleeding, abdominal pain. Successful ED SBCE duodenum or jejunum in 91.8% 90.7% aged <16 years ≥16 years, respectively (P = 0.6661), but total enteroscopy rate was higher first group (91.7%) than second (76.2%, P < 0.0001), whom impossible ingestion (87.3%) significantly more common prolonged lodging stomach (64.2%, 0.0010). PC CCE 84.1% 28.6%, thereafter confirmation colonoscopy 100% 61.5%, The height, weight, age cutoff points predicting spontaneous 132 cm, 24.8 kg, 9 2 months, respectively, years. Patients could not swallow SBCEs mainly due dysphagia (75.0%); those retained it esophagus cardiac disease (28.6%), etc. diabetes mellitus (15.7%), CONCLUSIONS: This large-scale study supports adult patients. UMIN000042020.