Diagnostic performance and safety of endoscopic ultrasound‐guided fine‐needle aspiration/biopsy for gallbladder lesions

• DOI: 10.1111/den.14576
• Publication Date: 2023-04-26T11:22:12Z
• Authors: Yasuhiro Kuraishi; Kazuo Hara; Shin Haba; Takamichi Kuwahara; Nozomi Okuno; Takafumi Yanaidani; Sho Ishikawa; Tsukasa Yasuda; Masanori Yamada; Toshitaka Fukui; Nobumasa Mizuno
• Keywords: Endoscopic Ultrasound

Objectives Endoscopic ultrasound‐guided fine‐needle aspiration and biopsy (EUS‐FNA/FNB) is not fully established as a pathological sampling tool for gallbladder lesions due to limited evidence. We therefore aimed clarify the effectiveness safety of this procedure in large‐population cohort. Methods This study retrospectively evaluated diagnostic yield EUS‐FNA/FNB accurately differentiating between benign malignant lesions. Puncture targets included mass, lymph node, liver mass. Adverse events factors associated with accuracy were analyzed well. Results In 187 patients undergoing EUS‐FNA/FNB, 18 169 identified. Overall adequacy was 98% (184/187). The 97% (182/187), sensitivity (164/169), specificity 100% (18/18). A single postprocedural complication (minor bleeding) recorded one patient. cases malignancy, 203 sites punctured primary mass ( n = 94), node 79), metastatic 30). No significant difference found among puncture P 0.70). having specimens obtained from those targeting invasion significantly higher than that other (98% vs. 83%, < 0.01). Conclusion demonstrated clinical usefulness diagnosis lesions, high low incidence adverse events. Targeting site infiltration may improve rate