Habituation and novelty detection fNIRS brain responses in 5‐ and 8‐month‐old infants: The Gambia and UK

• DOI: 10.1111/desc.12817
• Publication Date: 2019-02-16T14:23:40Z
• Authors: Sarah Lloyd‐Fox; Anna Blasi; Samantha McCann; Maria Rozhko; Laura Katus; Luke Mason; Topun Austin; Sophie E. Moore; Clare E. Elwell
• Keywords: Neurocognitive

The first 1,000 days of life are a critical window vulnerability to exposure socioeconomic and health challenges (i.e. poverty/undernutrition). Brain Imaging for Global Health (BRIGHT) project has been established deliver longitudinal measures brain development from 0 24 months in UK Gambian infants assess the impact early adversity. Here results Habituation-Novelty Detection (HaND) functional near-infrared spectroscopy (fNIRS) task at 5 8 presented (N = 62 UK; N 115 Gambia). In cohort distinct patterns habituation recovery response novelty seen, becoming more robust age. Gambia, an attenuated is evident: larger number trials required before sufficiently suppresses relative during trials. Furthermore, not evident or As this study continues parallel collection socioeconomic, caregiving, nutrition data will allow us stratify how individual trajectories associate with different risk factors adaptive mechanisms greater depth. Given increasing interest use neuroimaging methods within global neurocognitive developmental studies, provides novel cross-culturally appropriate paradigm responses associated attention learning across development.