Impact of gestational diabetes mellitus and high maternal weight on the development of diabetes, hypertension and cardiovascular disease: a population‐level analysis

• DOI: 10.1111/dme.12635
• Publication Date: 2014-11-19T07:18:12Z
• Authors: P. Kaul; A. Savu; K. A. Nerenberg; L. E. Donovan; C. L. Chik; E. A. Ryan; J. A. Johnson
• Keywords: Adult; Adolescent; Alberta; Cohort Studies; 03 medical and health sciences; 0302 clinical medicine; Pregnancy; Diabetes Mellitus; Humans; Longitudinal Studies; Registries; Retrospective Studies; 2. Zero hunger; Incidence; Maternal Nutritional Physiological Phenomena; Middle Aged; Overweight; 3. Good health; Pregnancy Complications; Diabetes, Gestational; Cross-Sectional Studies; Cardiovascular Diseases; Hypertension; Female

Abstract Aims To examine the association between gestational diabetes mellitus ( GDM ) and high maternal weight risk of development chronic disease. Methods Women with singleton deliveries April 1999 March 2010 in Alberta, Canada, were categorized according to pre‐pregnancy (overweight ≥ 91 kg) status. Obstetric neonatal outcomes, as well long‐term incidence diabetes, hypertension cardiovascular disease examined. Results Of 240 083 women, 213 765 (89%) had no not overweight (reference group), 17 587 (7.3%) only, 7332 (3%) only 1399 (0.6%) overweight. Significant differences Caesarean section rates, induction rates birthweight observed across four groups. During a median follow‐up 5.3 years, was 36% overweight, 18.8% 4.8% 1.1% reference group. With respect disease, group highest (26.8% 3.1%, respectively) lowest (5.8% 1.0%, respectively). However, similar (14.9% 1.9%, groups 1.5%, Conclusions Not surprisingly, presence both compounds developing diabetes. alone appears suggesting need for effective interventions manage these conditions improve health patients.