Performance of a factory‐calibrated, real‐time continuous glucose monitoring system during elective abdominal surgery

• DOI: 10.1111/dom.14073
• Publication Date: 2020-06-13T09:01:50Z
• Authors: Afroditi Tripyla; David Herzig; Dehais Joachim; Christos T. Nakas; Franziska Amiet; Andreas Andreou; Beat Gloor; Andreas Vogt; Lia Bally
• Keywords: Interquartile range

Abstract We assessed the performance of factory‐calibrated, sixth‐generation continuous glucose monitoring (CGM) system Dexcom G6® (DexCom Inc., San Diego, California) during elective abdominal surgery. Twenty adults with (pre)diabetes undergoing surgery (>2 hours; 15 men, age 69 ± 13 years, glycated haemoglobin 53 14 mmol/mol) wore sensor from 1 week prior to until hospital discharge. From induction anaesthesia 2 hours post‐surgery, reference capillary values were obtained every 20 minutes using Accu‐Chek® Inform II meter (Roche Diabetes Care, Mannheim, Germany). The primary endpoint was mean absolute relative difference (ARD) between and method this period. In total, 1207 CGM/reference pairs obtained. peri‐operative period (523 pairs), SD median (interquartile range [IQR]) ARD 12.7% 8.7% 9.9 (6.3;15.9)%, respectively, 67.4% readings within International Organization Standardization 15197:2013 limits. CGM overestimated by 1.1 0.8 mmol/L (95% limits agreement −0.5;2.7 mmol/L). Clarke error grid zones A or B contained 99.2% (A: 78.8%; B: 20.4%). (IQR) availability 98.6 (95.9;100.0)%. No clinically significant adverse events occurred. conclusion, G6 device showed consistent acceptable accuracy surgery, opening new avenues for management.