Patterns of insulin therapy and insulin daily doses in children and adolescents with type 1 diabetes in Germany

• DOI: 10.1111/dom.14581
• Publication Date: 2021-10-22T03:36:04Z
• Authors: Louisa van den Boom; Karel Kostev
• Keywords: Insulin aspart; Insulin pump

To describe the different insulin therapy patterns and daily doses in children adolescents (aged 1-17 years) with type 1 diabetes.This cross-sectional study based on longitudinal prescription (LRx) database (IQVIA) included who received at least two prescriptions of same drug from January 2016 to 31 December 2019. The outcomes proportion patients pumps multiple injection therapy, human analogue use, as well doses. A multivariable linear regression model was used association between age, sex, drugs, dose.A total 22 512 (mean age: 13.5 years, 47.1% female) were included. using pump decreased 72.6% (females) 73.0% (males) age group younger than 6 years 30.8% 26.1% adolescents. Insulin aspart most common short-acting insulin, users increasing 56% 69%-70% 13-17 group. dose 10 units lower (MDI) (P < .001).We found a marked dependency for strong increase observed youngest frequently insulin. higher shown MDI versus pump, along significant dependency.