Baseline and cumulative Chinese visceral adiposity index and diabetic kidney disease: A prospective cohort study

• DOI: 10.1111/dom.16184
• Publication Date: 2025-01-15T08:40:27Z
• Authors: Ming Sun; Qitong Liu; Yang Liu; Ning Ning; Jin Zhou; Di Zhou; Huancong Zheng; Shouling Wu; Jingli Gao; Yanan Ma

Abstract Background Diabetic kidney disease (DKD) makes up nearly half of all chronic cases and is a major cause mortality for people with diabetes. However, the study association longitudinal Chinese visceral adiposity index (CVAI) DKD still missing. Methods This prospective cohort included 7874 diabetes patients from Kailuan study. These participants had complete repeated waist circumference, body mass index, triglycerides high‐density lipoprotein cholesterol measurements that formed continuous CVAI records. was defined by increased proteinuria or decreased estimated glomerular filtration rate (eGFR), preceded Cox proportional hazard regression models were used to examine associations between baseline cumulative risk DKD. Results There positive level, whether cumulative, incidence among diabetic ( p log‐rank tests <0.001). Compared low high level positively associated (HR: 1.24, 95% CI: 1.09–1.42), as well 1.62, 1.29–2.04). In addition, assumption linearity both P ‐nonlinear = 0.264, overall <0.001) 0.765, incident satisfied. Conclusions Higher are higher finding suggests health benefits levels importance its regular surveillance individuals