Ratio of Acceleration Time to Ejection Time for Assessing Aortic Stenosis Severity

• DOI: 10.1111/echo.12978
• Publication Date: 2015-05-22T06:03:20Z
• Authors: Sergio Gamaza‐Chu...; Santiago Camacho‐...; Rocío Toro‐Cebada; Alberto Giráldez‐...; Javier Benezet‐Ma...; José Carlos Varga...
• Keywords: Male; Acceleration; Reproducibility of Results; Aortic Valve Stenosis; Sensitivity and Specificity; Severity of Illness Index; Echocardiography, Doppler; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Aortic Valve; Image Interpretation, Computer-Assisted; Humans; Female; Algorithms; Aged

Inconsistencies in the grading of aortic valve stenosis are frequent (24-38%). Guidelines highlight waveform shape when discrepancies present. Our aim was to evaluate severity by ratio acceleration time ejection (AT/ET).Between January 2011 and 2013, patients with at least moderate (valve area < 1.5 cm(2) ) evaluated our echocardiography laboratory were enrolled. Clinical data recorded including symptoms attributable stenosis. Quantitative echocardiographic Doppler parameters as dynamics (ejection time) conventional parameters, usual test natriuretic peptides (NT-proBNP) analyzed.One hundred eight recruited (mean age 77 ± 7 years; 57% women). Comorbidity frequent: 85% hypertension, 59% diabetes, 31% chronic renal failure, 26% smokers, mean body mass index 30.0 6.6 kg/m(2) . Ninety-six (90%) symptomatic visit. Using a cutoff 0.35, AT/ET had sensitivity 77% specificity 100% discriminate patients. Serum value NT-proBNP higher > 0.35 (9885 3111 vs. 2600 1175, P 0.001). This showed good correlation indexed left ventricle (r = 0.60, 0.001), DVI -0.56, AVA -0.49, 0.001).Ejection through valve, particularly ratio, is useful tool for assessing severity, flow-independent