Development of the PSYCHS: Positive SYmptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS

• DOI: 10.1111/eip.13457
• Publication Date: 2023-08-29T06:58:18Z
• Authors: Scott W. Woods; Sophie Parker; Melissa J. Kerr; Barbara C. Walsh; S. Andrea Wijtenburg; Nicholas Prunier; Angela R. Nunez; Kate Buccilli; Catalina Mourgues...; Kali Brummitt; Kyle S. Kinney; Carli Trankler; Julia Szacilo; Beau‐Luke Colton; Munaza Ali; Anastasia Haidar; Tashrif Billah; Kevin Huynh; Uzair Ahmed; Laura L. Adery; Patricia J. Marcy; Kelly Allott; Paul Amminger; Celso Arango; Matthew R. Broome; Kristin S. Cadenhead; Eric Y. H. Chen; Jimmy Choi; Philippe Conus; Barbara A. Cornblatt; Louise Birkedal G...; Leslie E. Horton; Joseph Kambeitz; Tina Kapur; Matcheri S. Keshavan; Nikolaos Koutsoul...; Kerstin Langbein; Suzie Lavoie; Covadonga Martine...; Daniel H. Mathalon; Vijay A. Mittal; Merete Nordentoft; Ofer Pasternak; Godfrey D. Pearlson; Pablo A. Gaspar; Jai L. Shah; Stefan Smesny; William S. Stone; Gregory P. Strauss; Jijun Wang; Cheryl M. Corcoran; Diana O. Perkins; Jason Schiffman; Jesus Perez; Daniel Mamah; Lauren M. Ellman; Albert R. Powers; Michael J. Coleman; Alan Anticevic; Paolo Fusar‐Poli; John M. Kane; Rene S. Kahn; Patrick D. McGorry; Carrie E. Bearden; Martha E. Shenton; Barnaby Nelson; Monica E. Calkins; Larry Hendricks; Sylvain Bouix; Jean Addington; Thomas H. McGlashan; Alison R. Yung
• Keywords: Psychiatric Status Rating Scales; psychometrics; Psychotic Disorders; psychometric; 616; severity rating; Biological Psychiatry; Psychiatry and Mental health; Pshychiatric Mental Health; 150; Humans; Prodromal Symptoms; clinical high risk; early detection; ascertainment

AbstractAimTo harmonize two ascertainment and severity rating instruments commonly used for the clinical high risk syndrome for psychosis (CHR‐P): the Structured Interview for Psychosis‐risk Syndromes (SIPS) and the Comprehensive Assessment of At‐Risk Mental States (CAARMS).MethodsThe initial workshop is described in the companion report from Addington et al. After the workshop, lead experts for each instrument continued harmonizing attenuated positive symptoms and criteria for psychosis and CHR‐P through an intensive series of joint videoconferences.ResultsFull harmonization was achieved for attenuated positive symptom ratings and psychosis criteria, and modest harmonization for CHR‐P criteria. The semi‐structured interview, named Positive SYmptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS (PSYCHS), generates CHR‐P criteria and severity scores for both CAARMS and SIPS.ConclusionsUsing the PSYCHS for CHR‐P ascertainment, conversion determination, and attenuated positive symptom severity rating will help in comparing findings across studies and in meta‐analyses.