Ultra‐early hematoma growth in antithrombotic pretreated patients with intracerebral hemorrhage

• DOI: 10.1111/ene.13458
• Publication Date: 2017-09-14T14:04:51Z
• Authors: J. Roquer; R. M. Vivanco‐Hid...; J. Capellades; A. Ois; E. Cuadrado‐Godia; E. Giralt‐Steinhauer; C. Soriano‐Tárraga; M. Mola‐Caminal; M. Serra‐Martínez; C. Avellaneda‐Gómez; J. Jiménez‐Conde; A. Rodríguez‐Camp...
• Keywords: Interquartile range; Vitamin K antagonist

Background and purpose Patients with acute intracerebral hemorrhage ( ICH ) pretreated antithrombotic drugs may have increased early hematoma growth, which would increase mortality risk. The effect of antiplatelet AP vitamin K antagonist VKA pretreatment on ultra‐early growth uHG its relationship in patients supratentorial was analyzed. Methods This is an observational retrospective study a prospective register 197 first computed tomography CT scan taken <6 h from symptom onset. volume calculated by the ABC /2 formula baseline volume/onset‐to‐ time ml /h) formula. analysis took into account patient's (none, or between very‐early (first 24 h) 3‐month mortality. Results In group, 50 (25.4%) were treated 37 (18.8%) . median (interquartile range 25–75) 19.7 ml/h (2.9–44.8) for patients, 16.2 (5.1–42.5) 8.4 (2.4–21.8) non‐pretreated P = 0.019. higher [42.1 (20.1–79.6)] total [28.0 (15.8–52.5)] compared survivors [3.9 (1.5–10.4)], < 0.0001. Adjusted severity previous functional status, independent factor related to 0.028) 0.014). Conclusions antithrombotics much , explain these untreated patients.