Scale for the assessment and rating of ataxia: Age‐dependent performance of healthy adults

• DOI: 10.1111/ene.15596
• Publication Date: 2022-10-10T15:09:50Z
• Authors: Marcus Grobe‐Einsler; Alina Schmidt; Tamara Schaprian; Ina R. Vogt; Thomas Klockgether
• Keywords: Clinical neurology

The Scale for Assessment and Rating of Ataxia (SARA) is a widely used clinical scale. objective was to study the age dependence SARA in healthy adults define age-specific cut-off values differentiate from ataxic individuals.Data 390 individuals 119 spinocerebellar ataxia patients were analyzed. scores mapped on functional (fSARA). Age-adjusted determined by receiver operating characteristic curve analysis.The value 3 1.5 fSARA. Older had higher (4.5 60-69 years 6.5 70-79 years). fSARA are 1 18-29, 30-39 50-59 years, 2 40-49 years. Sensitivity specificity than fSARA.In this study, age-dependent defined results may be relevant design future preventive trials ataxias that use conversion as an outcome.