Asymptomatic parenchymal haemorrhage following endovascular treatment: Impact on functional outcome in patients with acute ischaemic stroke

• DOI: 10.1111/ene.16112
• Publication Date: 2023-11-01T13:33:02Z
• Authors: Clara Toscano‐Prat; José Pablo Martín...; Marina Guasch‐Jim...; Anna Ramos‐Pachón; Joan Martí‐Fàbregas; Nerea Blanco‐Sanr...; Melissa Fabiola C...; María Constanza D...; Alejandro Martíne...; Luis Prats‐Sánchez; Rebeca Marín‐Bueno; Ana Aguilera‐Simón; Álvaro Lambea‐Gil; Garbiñe Ezcurra‐Díaz; Pol Camps‐Renom
• Keywords: Stroke

Abstract Background and purpose In patients with acute ischaemic stroke (AIS), haemorrhagic transformation (HT) following endovascular treatment (EVT) is associated poor functional outcome. However, the impact of asymptomatic HT, not linked to neurological deterioration in phase, unknown. We aimed investigate PH1 (aPH1) PH2 (aPH2) subtypes HT on outcome treated EVT. Methods conducted a retrospective study AIS who were consecutively admitted our comprehensive centre between January 2019 December 2022, underwent collected clinical, radiological, procedural data. HTs categorized according Heidelberg classification. The primary was shift modified Rankin Scale (mRS) at 3 months follow‐up. performed bivariate multivariable ordinal regression analyses test association aPH1/aPH2 Results included 314 (mean age = 72.5 years [SD 13.6], 171 [54.5%] women). detected 54 (17.2%) HT; 23 (7.3%) classified as (11 asymptomatic) 17 (5.4%) (16 asymptomatic). adjusted common odds ratio for aPH2 worsening 1 point 3‐month mRS 3.32 (95% confidence interval 1.16–9.57, p 0.026). No observed aPH1. also independently lower achieving favourable (mRS 0–2). Neither aPH1 nor mortality. Conclusions EVT, unfavourable