Imbalanced optimal feedback motor control system in spinocerebellar ataxia type 3

• DOI: 10.1111/ene.16368
• Publication Date: 2024-06-24T07:46:07Z
• Authors: Leinian Li; Hui Chen; LiHua Deng; YongHua Huang; YuHan Zhang; YueYuan Luo; PeiLing Ou; LinFeng Shi; LiMeng Dai; Wei Chen; HuaFu Chen; Jian Wang; Chen Liu
• Keywords: Neocortex; Pyramidal tracts; Motor Control

Human motor planning and control depend highly on optimal feedback systems, such as the neocortex-cerebellum circuit. Here, diffusion tensor imaging was used to verify disruption of circuit in spinocerebellar ataxia type 3 (SCA3), circuit's correlation with SCA3 dysfunction investigated.