An investigation of anthelmintic efficacy against strongyles on equine yards in Scotland

• DOI: 10.1111/evj.12079
• Publication Date: 2013-03-13T08:01:56Z
• Authors: C. H. Stratford; H. E. Lester; K. J. Pickles; B. C. McGorum; J. B. Matthews
• Keywords: Moxidectin; Pyrantel; Eggs per gram

Summary Reasons for performing study Cyathostomins comprise 50 helminth species, considered the most problematic equine endoparasites. Three classes of anthelmintic are currently licensed their control, namely benzimidazoles (fenbendazole), tetrahydropyrimidines (pyrantel) and macrocyclic lactones (ivermectin moxidectin). Anthelmintic resistance in cyathostomins is common. With no new expected near future, it essential to determine efficacy available anthelmintics inform future control programmes. Objectives To all 3 against strongyles equids on livery yards east central S cotland. Study design testing using faecal egg count reduction test (FECRT). Methods FECRT s were performed with initial strongyle counts ( FEC s) ≥50 eggs per gram. Efficacy was determined by comparing pretreatment (Day 0) 14 days post treatment 14) s. The following chemicals tested: fenbendazole, pyrantel, ivermectin moxidectin. Group arithmetic mean FECR >90% fenbendazole >95% moxidectin, represented efficacy, whereas lower indicated potential resistance. Results A total 447 15 yards, as follows (the numbers parentheses represent number each tested on): 55 (7 yards) 111 (8 163 (13 118 (10 Fenbendazole documented (range , 15.8–83.4%), pyrantel (90.4–99.6%), (99.5–100%) moxidectin (99.4–100%) had acceptable efficacy. Conclusions Reduced widespread, found after Overall, efficacies higher than reported previously E urope USA potentially reflecting differences management use surveyed. Potential relevance cotland should be questioned. Targeted encouraged reduce reliance lactones. Further work correlate practices presence warranted. ummary C hinese – see upporting information.