High bacterial colonization and lipase activity in microcomedones

• DOI: 10.1111/exd.14069
• Publication Date: 2019-12-21T04:20:35Z
• Authors: Gwendal Josse; Céline Mias; Jimmy Le Digabel; Jérôme Filiol; Célia Ipinazar; Aurélie Villaret; Caroline Gomiero; Marc Bevilacqua; Daniel Redoules; Thérèse Nocera; Jean-Hilaire Saurat; Etienne Gontier
• Keywords: Propionibacterium Acnes

Although acne vulgaris has a multifactorial aetiology, comedogenesis and bacteria colonization of the pilosebaceous unit are known to play major role in onset inflammatory lesions. However, many aspects remain poorly understood such as where when is early stage Propionibacterium acnes follicular unit? Our research aimed at providing precise analysis microcomedone's structure better understand interplay between units, therefore, its formation