Feasibility of daylight‐mediated photodynamic therapy for actinic keratosis throughout the year in Central and South America: a meteorological study

• DOI: 10.1111/ijd.13256
• Publication Date: 2016-04-10T17:45:43Z
• Authors: Beni Grinblat; Gaston Galimberti; Gonzalo Pantoja; Gloria Sanclemente; Miguel Lopez; Daniel Alcala; Luís Torezan; Delphine Kerob; Thierry Pascual; Edgardo Chouela
• Keywords: Daylight; Actinic keratosis; Sunlight; Tolerability

Summary Background Daylight‐mediated photodynamic therapy ( DL ‐ PDT ) is an efficacious treatment option for thin actinic keratosis AK that offers advantages over conventional in terms of tolerability, duration, and cost. A clinical study conducted Australia determined the mean irradiance during a 2‐hour exposure to be 305.8 W/m 2 (range: 40–585 ). The protoporphyrin IX light dose influenced by latitude, weather conditions, time year. recent meteorological data concluded can performed effectively throughout year Australia. Objectives Based on same hypothesis applying methodology, present investigated suitability daylight perform DL‐PDT Central South America. Methods Solar radiation were gathered analyzed assess (light intensity) full across 32 geographical locations Results minimum average daily solar reported was above all Annual averages ranged from 578 Chihuahua, Mexico, 321 Puerto Montt, Chile. Conclusions America given conditions permit comfortable direct daylight.