Urodynamic analysis of the impact of diabetes mellitus on bladder function

• DOI: 10.1111/iju.13935
• Publication Date: 2019-03-19T22:51:01Z
• Authors: Tsuyoshi Majima; Yoshihisa Matsukawa; Yasuhito Funahashi; Shun Takai; Masashi Kato; Tokunori Yamamoto; Momokazu Gotoh
• Keywords: Contractility

Objectives To analyze sequential changes of diabetic cystopathy based on urodynamic data in patients with diabetes mellitus. Methods Participants included male who underwent a pressure flow study at Nagoya University Graduate School Medicine, Nagoya, Japan, from April 2005 to October 2016. Patients previous history lower urinary tract dysfunction were excluded. Bladder was categorized into four patterns: (i) normal; (ii) detrusor overactivity normal contractility; (iii) hyperreflexia/impaired and (iv) underactivity. The patterns evaluated according the presence retinopathy nephropathy, which correlated mellitus duration. Furthermore, association clinical factors voiding function, as well sensory investigated. Results A total 57 enrolled. Detrusor contractility seen only cases neither nor whereas prevalence pattern highest retinopathy. underactivity found frequency both nephropathy. On multivariate analysis, existence significantly bladder index. analysis showed that first desire volume maximum cystometric capacity positively post‐void residual urine volume, also negatively efficiency independent Conclusions Diabetes have diverse progressive stage. An optimal screening program is necessary detect manage an early