Chromium allergy: significance of both Cr(III) and Cr(VI)

• DOI: 10.1111/j.0105-1873.2003.0230.x
• Publication Date: 2004-01-28T16:43:48Z
• Authors: M. B. Hansen; J. D. Johansen; T. Menné
• Keywords: Contact Allergy

Most studies investigating chromium allergy have been performed with Cr(VI). However, real exposure to from leather products includes both Cr(III) and We determined compared the minimum elicitation threshold (MET) concentration for Cr(VI) in Cr(VI)-sensitive patients. In addition, reactions combinations of were elicited by alone. Dilution series applied Finn Chambers on back 18 The patches left 2 days readings done 2, 3 7. MET10% was calculated dose-response curves be 0.18 microg/cm2/48 h (6 p.p.m.) 0.03 (1 p.p.m.), respectively. No significant differences response combined solutions versus single found. concluded play an important role allergy, because capable eliciting eczema at low concentrations. Rather than regarding dermatitis as a result alone, it may more correct consider allergy.