Plasma levels of 8-methoxypsoralen after bath-PUVA for psoriasis: relationship to disease severity

• DOI: 10.1111/j.1365-2133.1995.tb02489.x
• Publication Date: 2010-07-21T15:25:42Z
• Authors: M. I. GÓMEZ; J. M. AZAÑA; I. ARRANZ; A. HARTO; A. LEDO
• Keywords: PUVA therapy; Methoxsalen; Plasma levels

Plasma levels of 8-methoxypsoralen (8-MOP) were determined by high-pressure liquid chromatography in 19 patients with psoriasis who receiving bath-PUVA treatment, at different time points after the psoralen bath. The 8-MOP varied between < 5 ng/ml (lower limit detection) and 34 ng/ml, we found a relationship plasma severity disease.