Spatio‐temporal accumulation of microRNAs is highly coordinated in developing plant tissues

• DOI: 10.1111/j.1365-313x.2006.02766.x
• Publication Date: 2006-05-25T08:44:08Z
• Authors: Anna Válóczi; Éva Várallyay; Sakari Kauppinen; József Burgyán; Zoltán Havelda
• Keywords: Organogenesis

MicroRNAs (miRNAs) are an abundant class of small, endogenous non-protein-coding RNAs, approximately 21 nucleotides in length, that modulate the expression animal and plant target genes at post-transcriptional level. Recent work has shown miRNA-based gene regulation plays a crucial role pathways involved growth development. However, knowledge about timing spatial miRNA is still limited. Here we used situ analysis to demonstrate miRNAs accumulate spatially temporally highly restricted manner Nicotiana benthamiana Arabidopsis thaliana. The presence seven investigated was characteristic developing organs, implying cell-fate establishment, differentiation cell-cycle progression. Spatial analyses revealed six studied were present vascular bundles, suggesting mobile phloem could contribute coordination organogenesis obvious absence miR167 bundles represented exception this observation, active process regulating system. Taken together, our results imply organized accumulation pivotal fine-tuning