Influence of Orally Administered Antibiotics on anti‐T Agglutinin of Normal Subjects and of Cirrhotic Patients

• DOI: 10.1111/j.1423-0410.1974.tb02418.x
• Publication Date: 2009-03-06T01:42:31Z
• Authors: V. Boccardi; D. Attinà; Gabriella Girelli
• Keywords: Liver Cirrhosis; Antigens, Bacterial; Erythrocytes; Neuraminidase; Neomycin; Blood Proteins; Hemagglutination Tests; Antibodies, Bacterial; 3. Good health; Epitopes; 03 medical and health sciences; Bacitracin; 0302 clinical medicine; Enterobacteriaceae; Agglutinins; Isoantibodies; Lectins; Antibody Formation; Humans; gamma-Globulins

Abstract. Anti‐T agglutinin was studied in normal healthy subjects and cirrhotic patients before after oral administration of antibiotics depressing intestinal microbial flora. After antibiotic treatment anti‐T levels were significantly reduced. These observations show that bacterial antigens origin are likely to be responsible for production there must common determinants between them T antigen red blood cells. It is not sure whether the previously reported increase liver cirrhosis favour hypothesis hypergammaglobulinaemia this condition due failure diseased trap gut‐derived antigens.