Importance of White Blood Cells in Platelet Storage1

• DOI: 10.1111/j.1423-0410.1984.tb01570.x
• Publication Date: 2009-03-05T23:21:35Z
• Authors: Jerome L. Gottschall; Victoria L. Johnston; Lanette Rzad; Alfred J. Anderson; Richard H. Aster
• Keywords: Mean platelet volume; White blood cell; Blood product

Abstract. Platelet concentrates from 290 healthy donors collected in CPD anticoagulant and PL‐146 polyvinylchloride containers were stored for 72 h at 22±0.5°C under standard conditions to investigate variables affecting the quality of platelets. In addition expected inverse relationship between pH platelet count (p < 0.001), a significant correlation white blood cell (WBC) was also noted 0.01). Platelets female developed lower than those male donors; this difference could not be accounted by any analyzed other sex. To WBC further, 15 units platelet‐rich plasma (PRP) depleted WBCs slow centrifugation prior being 3 days. This resulted mean loss 10% platelets 75% WBCs. The average post‐storage WBC‐poor (7.06 ± 0.02) significantly higher that routinely prepared containing same number (6.54 0.43) 0.001). Production lactic acid consumption glucose markedly diminished leukocyte‐poor concentrates. These data suggest affect metabolic activity can improved reducing contaminating leukocytes. Measurement leukocytes may important control