Preattentive dysfunction in major depression: A magnetoencephalography study using auditory mismatch negativity

• DOI: 10.1111/j.1469-8986.2008.00748.x
• Publication Date: 2008-11-25T21:58:13Z
• Authors: Yuichi Takei; Sumie Kumano; Suguru Hattori; Toru Uehara; Yuki Kawakubo; Kiyoto Kasai; Masato Fukuda; Masahiko Mikuni
• Keywords: Magnetoencephalography; Depression

Information processing deficits in major depressive disorder have been infrequently examined electrophysiologically. Its preattentive and sensory information was using mismatch field (MMNm) P1m components, respectively, by magnetoencephalography. Fourteen patients 19 healthy volunteers participated the study. MMNm elicited response to duration frequency changes of pure-tone stimuli a vowel across-category change. The magnetic global power (mGFP) significantly smaller than volunteers, although that did not differ between two groups. at level is impaired functionally disorder, this dysfunction due lower processing.