Complications of Diagnostic and Therapeutic Ercp: A Prospective Multicenter Study

• DOI: 10.1111/j.1572-0241.2001.03594.x
• Publication Date: 2004-03-29T10:54:13Z
• Authors: E Masci; G Toti; A Mariani; S Curioni; A Lomazzi; M Dinelli; G Minoli; C Crosta; U Comin; A Fertitta; A Prada; Rubis G Passoni; P A Testoni
• Keywords: Major duodenal papilla; Perforation; Therapeutic Endoscopy

Diagnostic and therapeutic endoscopic retrograde cholangiopancreatography (ERCP/ES) can be associated with unforeseeable complications, especially when involving postprocedural pancreatitis. The aim of the study was to investigate risk factors for complications ERCP/ES in a prospective multicentric study.One hundred fifty variables were prospectively collected at time before hospital discharge over 2 years, consecutive patients undergoing procedure nine units Lombardy region Italy. More than 150 ERCPs performed each center per year by single operator or team no more three endoscopists.Two thousand four sixty-two procedures performed; 18 discharged because papilla Vater not reached (duodenal obstruction, previous gastrectomy, etc.). Two forty-four considered 2103 patients. Overall occurred 121 (4.95% cases): pancreatitis 44 (1.8%), hemorrhage 30 (1.13%), cholangitis 14 (0.57%), perforation during ES others (0.57%); deaths (0.12%). In multivariate analysis, following significant factors: a) pancreatitis, age (< = 60 yr), use precutting technique, failed clearing biliary stones, b) hemorrhage, precut sphincterotomy obstruction orifice Vater.The results our further contribute assessment related ERCP/ES. It is crucial identify high reduce procedures.