SERUM IMMUNOGLOBULINS AND LYMPHOCYTE SUBPOPULATIONS DERANGEMENT IN TURNER'S SYNDROME

• DOI: 10.1111/j.1744-313x.1981.tb00938.x
• Publication Date: 2007-04-02T23:40:54Z
• Authors: E. Cacciari; M. Masi; Maria Pia Fantini; F. Licastro; A. Cicognani; P. Pirazzoli; Maria Pia Villa; F. Specchia; A. Forabosco; C. Franceschi; L. Martoni
• Keywords: Derangement

SUMMARY Abnormalities of the proportions peripheral blood lymphocyte subpopulations and immunoglobulin serum levels were found in twenty patients affected by Turner's syndrome. A slight but significantly decreased percentage circulating T B cells, an increased null cells a vitro , responsiveness lymphocytes to phytohaemagglutinin, concanavalin pokeweed mitogen syndrome patients. IgG level was comparison with age‐matched fifty‐seven normal males females IgM intermediate between female male values; monosomy had concentration very close values. The derangement subpopulations, probably related aneuploidy, does not seem be severe one it could account for abnormalities association immunological disorders such as autoimmune diseases. role X chromosome on is discussed.