Long term performance and safety of His bundle pacing: A multicenter experience

• DOI: 10.1111/jce.14063
• Publication Date: 2019-07-16T12:37:27Z
• Authors: Francesco Zanon; Mohamed Abdelrahman; Lina Marcantoni; Angela Naperkowski; Faiz A Subzposh; Gianni Pastore; Enrico Baracca; Graziano Boaretto; Paola Raffagnato; Antonella Tiribello; Gopi Dandamudi; Pugazhendhi Vijay...
• Keywords: Interquartile range; Lead (geology)

Several single-center short-term studies have demonstrated the feasibility, safety, and positive clinical outcomes of permanent His bundle pacing (HBP). We performed a retrospective study to evaluate long-term technical safety performances HBP in large population pacemaker patients from two different centers.The analysis includes 844 (345 female, mean age = 75 ± 9 years) who underwent successful for indications 2004 2016. The main endpoints were long term electrical including threshold, sensing, impedance, freedom related complications. indication was AV Block 348 (41.2%) patients, sinus node disease 147 (17.4%), any bradycardia with atrial fibrillation 335 (39.7%) need cardiac resynchronization therapy 14 (1.7%) patients. Mean capture thresholds sensed R waves 1.6 V 5.8 mV, respectively at implant 2.0 6.1 mV chronic follow-up. During median follow up 3 years (interquartile range 1-6 years), free complication 91.6% In first 368 achieved using deflectable curve delivery system, while 476 fixed sheath. A significant difference found (2.4 1.0 1.7 1.1 V, P < .001, respectively) complications (11.9% 4.2%, between groups.Permanent safe effective during curved sheath offered significantly better parameters reliability over time. results this multicenter are consistent recent studies.