Chagas disease is associated with a worse prognosis at 1‐year follow‐up after implantable cardioverter‐defibrillator for secondary prevention in heart failure patients

• DOI: 10.1111/jce.14164
• Publication Date: 2019-09-10T04:10:56Z
• Authors: Rodrigo M. Vieira...; Diogo F. C. de Az...; Yasmin M. Lira; Natalia F. Cardos...; Luiz C. S. Passos
• Keywords: Chagas Disease; Ischemic Cardiomyopathy

There are conflicting data regarding the efficacy of implantable cardioverter-defibrillator (ICD) in Chagas disease (CD) patients. This study aims to evaluate short-term outcome after ICD for secondary prevention, a population where CD is prevalent cause heart failure (HF).Consecutive patients with HF and reduced left ventricular ejection fraction (LVEF), who underwent implantation prevention SCD. Clinical demographic were collected investigate mortality predictors at 1 year. During period, 117 implantation, which 108 included. The most frequent causes was CD: 52 (48.1%) ischemic cardiomyopathy: 20 (18.5%). non-Chagas well balanced-male: 32 (61.5%) vs 38 (67.9%), P = .548; age: 59.2 (±10.9) 56.8 (±13.4), .681; LVEF: 34.1 (±0.2) 31.3 (±8.7), .064, respectively. At mean follow-up 15.7 months, overall occurred 14 (12.9%) patients, higher incidence cardiomyopathy, 11 (21.2%) 3 (5.4%), .021 (log-rank). In multivariate analysis, remained as an independent predictor death (hazard ratio: 4.62, confidence interval [95% CI]: 1.27-16.81, .021).CD associated poor submitted when compared other etiologies. this specific population, indication should be individualized, considering worst prognosis these