Relationship between thyroid function and elevated blood pressure in euthyroid adults

• DOI: 10.1111/jch.13369
• Publication Date: 2018-09-08T13:28:01Z
• Authors: Yeqing Gu; Lixiao Zheng; Qing Zhang; Li Liu; Ge Meng; Zhanxin Yao; Hongmei Wu; Yang Xia; Xue Bao; Hongbin Shi; Honglei Wang; Haiyan Xu; Shaomei Sun; Xing Wang; Ming Zhou; Qiyu Jia; Kun Song; Kaijun Niu
• Keywords: Quartile; Thyroid-stimulating hormone

Thyroid hormones (THs) have profound effects on cardiovascular functions, suggesting that THs may contribute to the development of elevated blood pressure (BP). Few studies, however, systematically assessed relationship between and BP. We therefore conducted a cross‐sectional study examine how serum concentrations are related prevalence BP in euthyroid population. This (n = 12 487) was performed Tianjin, China. Serum free triiodothyronine (FT3), thyroxine (FT4), thyroid‐stimulating hormone (TSH) levels were measured by chemiluminescence immunoassay. Elevated defined according JNC 8 criteria. Analysis covariance multiple logistic regression models used assess relationships FT3, FT4, TSH quartiles The multivariable‐adjusted odds ratios (95% confidence interval) for gradual increase quartiles, when compared lowest 1.08 (0.97, 1.21), 1.24 (1.12, 1.39), 1.32 (1.18, 1.47); 1.18 (1.06, 1.32), 1.31), (1.11, 1.38); 1.06 (0.96, 1.19), (0.95, 1.18), 1.03 (0.93, 1.15), respectively. Our demonstrated FT3 FT4 positively adults, but no significant found