Central rather than brachial pressures are stronger predictors of cardiovascular outcomes: A longitudinal prospective study in a Chinese population

• DOI: 10.1111/jch.13838
• Publication Date: 2020-03-10T06:44:37Z
• Authors: Ying Dong; Linlin Jiang; Xin Wang; Zuo Chen; Linfeng Zhang; Zugui Zhang; Congyi Zheng; Yuting Kang; Zengwu Wang; Huiqing Cao; Xiaoxia Wang; Tian Fang; Xiaoyan Han; Zhe Li; Ye Tian; Lihang Dong; Fengyu Sun; Fucai Yuan; Xin Zhou; Yunyang Zhu; Yi He; Qingping Xi; Ruihai Yang; Jun Yang; Yong Ren; Maiqi Dan; Yiyue Wang; Daming Yu; Ru Ju; Dongshuang Guo; Dahua Tan; Zhiguo Zheng; Jingjing Zheng; Yang Xu; Dongsheng Wang; Tao Chen; Meihui Su; Yongde Zhang; Zhanhang Sun; Chen Dai
• Keywords: Pulse pressure

Abstract The purpose of this study was to assess the association blood pressure (BP) measurements with risk cardiovascular disease (CVD) and examine whether central systolic BP (CSBP) predicts CVD better than brachial (SBP pulse [PP]). Based on a cross‐sectional conducted in 2009‐2010 follow‐up 2016‐2017 among 35‐ 64‐year‐old subjects China, we evaluated performance non‐invasively predicted CSBP over first events. Each measurement, individually jointly another entered into multivariate Cox proportional‐hazards models, predictability measurements. Mean age participants (n = 8710) 50.1 years at baseline. After median 6.36 years, 187 events occurred. stronger predictor for (CSBP, 1‐standard deviation increment HR 1.49, 95%CI: 1.31‐1.70). With SBP entering models jointly, 1.28 (1.04‐1.58) 1.22 (0.98‐1.50), respectively. PP 1.51 (1.28‐1.78) 0.98 (0.83‐1.15), For subgroup analysis, women, those hypertension obesity. In middle‐aged Chinese population, noninvasively estimated may offer advantages predict events, especially higher risk. These findings suggest prospective assessment as prevention treatment target further trials.