Association of Red Blood Cell Distribution Width With Carotid–Femoral Pulse Wave Velocity in a Southern Chinese Population

• DOI: 10.1111/jch.14964
• Publication Date: 2025-01-17T14:55:07Z
• Authors: Xing Yu; Yali Huang; Yunyun Su; Liangdi Xie
• Keywords: Chinese population; Association (psychology)

Red blood cell distribution width (RDW) has recently been recognized as a novel biomarker associated with various cardiovascular conditions. This study aims to investigate the relationship between RDW and carotid-femoral pulse wave velocity (cfPWV) in southern Chinese population. A total of 4916 patients were initially enrolled from First Affiliated Hospital Fujian Medical University January 2016 December 2022. Based on criteria inclusion exclusion, 2830 included this study. Body weight, height, pressure measured, clinical biochemical tests recorded. cfPWV was assessed using non-invasive automatic device. Spearman's correlation analysis, generalized linear regression multivariable logistic regression, stratified analysis conducted assess cfPWV. Participants into four subgroups based quartiles: Q1 (RDW ≤ 12.80%), Q2 (12.80% < 13.40%), Q3 (13.40% 14.10%), Q4 > 14.10%). significant increase age, systolic pressure, cfPWV, HbA1c levels observed higher quartiles. Both revealed association Specifically, compared lowest quartile, risk cfPWV≥10 m/s increased by 56% highest quartile (odds ratio = 1.564, p 0.001). persisted particularly among elderly, hypertensive who not taking medication, those medication but had poor control. The plasma level significantly population, older adults individuals hypertension, suggesting potential marker for arterial stiffness.