Role of obesity on the thickness of primary cutaneous melanoma

• DOI: 10.1111/jdv.12515
• Publication Date: 2014-04-21T06:53:37Z
• Authors: F. Skowron; F. Bérard; B. Balme; D. Maucort‐Boulch
• Keywords: Nodular melanoma; Univariate analysis

Abstract Background Thick primary cutaneous melanoma ( PCM ) is associated with older age, male sex, being single, a low educational level, self‐detection and general practice detection, nodular NM acral lentiginous ALM types; are found in the head–neck lower limb locations. Obesity plays direct role on tumour growth, as it has been shown animal models, but its thickness of remains unknown. Objectives We investigated impact obesity invasive . Methods A cross‐sectional study was performed prospective cohort for which we collected several clinical histological data already known to be thick Body Mass Index from new cases were referred dermatology department Valence. Results Four hundred twenty‐seven patients studied. In an univariate analysis, obesity, identification by patient or practitioner GP ), location cephalic extremity, non‐visible area body, type, ulceration. multivariate , ulceration, topography significantly melanoma. When including only features model, mode risk Conclusions independent factor For health policies, governments should pay greater attention detect obese patients. Our results encourage basic research tumoural growth mechanisms due