A fifth subtype of Kaposi's sarcoma, classic Kaposi's sarcoma in men who have sex with men: a cohort study in Paris

• DOI: 10.1111/jdv.14831
• Publication Date: 2018-01-29T20:19:08Z
• Authors: D. Denis; V. Seta; E. Regnier‐Rosencher; N. Kramkimel; J. Chanal; M.‐F. Avril; N. Dupin
• Keywords: Kaposi's sarcoma; Univariate analysis

Abstract Background Classic Kaposi's sarcoma ( CKS ) occurs predominantly among elderly men and is associated with sarcoma‐associated herpesvirus KSHV ). In low‐endemic countries, infects having sex MSM Objectives To describe a cohort of classic Kaposi in area for , to highlight the features identify prognostic factors. Methods Retrospective single‐centre study cases. We compared heterosexual patients. Then, we divided patients into two subgroups, those requiring systemic treatment others, performed univariate multivariate analyses determine aggressiveness . Results Between 2006 2015, seventy‐four were included. Mean age at diagnosis was 68.9 years; ratio (M/F) 6.4, 28% ; younger P = 0.02), less often originated from endemic areas < 0.0001). KS severe 0.04), required more local than one 0.03). On analysis, CD 4 T‐cell count > 500/mm 3 baseline reduced risk evolution. Conclusion First zone. fifth subtype : The found correlate prognosis.