Carbon dioxide insufflation during colonoscopy can significantly decrease post‐interventional abdominal discomfort in deeply sedated patients: A prospective, randomized, double‐blinded, controlled trial

• DOI: 10.1111/jgh.13181
• Publication Date: 2015-09-30T16:51:32Z
• Authors: Shuo‐Wei Chen; Chung‐Kun Hui; Jia‐Jang Chang; Tsung‐Shih Lee; Siu‐Cheung Chan; Cheng‐Hung Chien; Ching‐Chih Hu; Chih‐Lang Lin; Li‐Wei Chen; Ching‐Jung Liu; Cho‐Li Yen; Po‐Jen Hsieh; Cheng‐Kun Liu; Chih‐Sheng Su; Chia‐Ying Yu; Rong‐Nan Chien
• Keywords: Double blinded

CO2 has been reported to be absorbed from the bowel more rapidly than air, resulting in a discomfort reduction after colonoscopy. Its role deeply sedated patients is limited. This study was designed investigate efficacy and safety of insufflation during colonoscopy with propofol.A total 125 continuous were randomly assigned receive either (n = 63) or air 62) propofol-sedated Postcolonoscopy abdominal pain, distention, satisfaction assessed at 1, 3, 24 h procedure, proportions pain-free distention-free compared. Residual gas colon small evaluated 1 End-tidal O2 saturation measured for analysis.There significant difference between two groups regarding postcolonoscopy subjective (P < 0.001) 3 0.01) procedure. Patients' pain distention procedure significantly lower group 0.01). less 0.001). There no end-tidal levels before, during, procedure.Compared reduced improved patients' satisfaction. It safe use