Anatomical versus non‐anatomical resection for solitary hepatocellular carcinoma without macroscopic vascular invasion: A propensity score matching analysis

• DOI: 10.1111/jgh.13603
• Publication Date: 2016-09-27T03:52:53Z
• Authors: Hui Zhao; Chuang Chen; Shen Gu; Xiaopeng Yan; Wenjun Jia; Liang Mao; Yudong Qiu
• Keywords: Vascular invasion

Abstract Background and Aim The superiority of anatomical resection (AR) in patients with hepatocellular carcinoma compared non‐anatomical (NAR) remains controversial. We aimed to investigate the prognostic outcomes AR NAR for solitary (HCC) without macroscopic vascular invasion, using a propensity score matching (PSM) analysis. Methods A total 305 consecutive HCC invasion who underwent curative hepatectomy were included our study. PSM was performed order eliminate possible selection bias. Results By PSM, divided into propensity‐matched (PS‐AR) ( n = 114) (PS‐NAR) groups. 1‐year, 3‐year, 5‐year overall survival rates 90.4%, 77.7%, 65.7% PS‐AR 88.6%, 70.7%, 52.2% PS‐NAR P 0.053), respectively. recurrence‐free (RFS) 84.1%, 64.9%, 45.1% 75.4%, 48.1%, 31.0% 0.005), Multivariate analysis showed that ICG‐R15 0.022); Barcelona clinic liver cancer staging 0.044) microvascular (MVI; 0.005) independent risk factors rate, while type 0.027), surgical margin 0.039), MVI 0.024) RFS rate. Patients prone early recurrence marginal recurrence. Subgroup indicated rate significantly better than (surgical ≥ 1 cm) 0.025). Better observed 0.016). Conclusions Anatomical contributed improve analysis, especially MVI.