Clathrin is required for DNA damage repair

• DOI: 10.1111/jipb.13910
• Publication Date: 2025-04-04T11:11:36Z
• Authors: Tongbin Yang; Xuerui Lu; Leilei Duan; Lili Wang; Shunping Yan
• Keywords: DNA Damage Repair

Genetic screening in Arabidopsis reveals that clathrin, a well-known regulator of endocytosis, is required for homologous recombination, precise mechanism repairing DNA double- strand breaks. Notably, CLATHRIN LIGHT CHAIN 2 localizes the nucleus, suggesting clathrin has non-canonical functions nucleus.