Evaluating the genetic status of a closed colony of titi monkeys (Callicebus cupreus) using multigenerational pedigrees

• DOI: 10.1111/jmp.12331
• Publication Date: 2018-02-01T08:37:35Z
• Authors: Sree Kanthaswamy; Karen L. Bales
• Keywords: Male; 0106 biological sciences; 0301 basic medicine; 03 medical and health sciences; Animals, Laboratory; Animals; Genetic Variation; Female; Pitheciidae; 01 natural sciences; Pedigree

AbstractPedigree metrics are essential for investigating colony genetic structure. The genetic structure of a closed Callicebus cupreus colony was examined using multigenerational pedigrees. Inbreeding was low, but genetic drift caused the loss of founder genome representation. Pedigrees can be used to detect founder representation and prevent bottlenecks and allele loss.