Neurochemical correlates of synapse density in a Huntington's disease mouse model

• DOI: 10.1111/jnc.15714
• Publication Date: 2022-10-22T15:29:35Z
• Authors: Nicole Zarate; Katherine Gundry; Dahyun Yu; Jordan Casby; Lynn E. Eberly; Gülin Öz; Rocio Gomez‐Pastor
• Keywords: Neurochemical

Striatal medium spiny neurons are highly susceptible in Huntington's disease (HD), resulting progressive synaptic perturbations that lead to neuronal dysfunction and death. Non-invasive imaging techniques, such as proton magnetic resonance spectroscopy (