The healing effect of Wharton's jelly stem cells seeded on biological scaffold in chronic skin ulcers: A randomized clinical trial

• DOI: 10.1111/jocd.12931
• Publication Date: 2019-05-25T05:40:30Z
• Authors: Seyedeh‐Sara Hashemi; Ali Akbar Mohammadi; Hamed Kabiri; Mohammad Reza Has...; Mahdokht Mahmoodi; Masood Amini; Davood Mehrabani
• Keywords: Wharton's jelly; Chronic wound; Amnion

Summary Background Chronic wound or nonhealing ulcer is essentially a that does not progress normally through the healing process. This study assessed effect of umbilical cord Wharton's jelly stem cells seeded on biological scaffold in chronic skin ulcers. Materials and Methods In randomized clinical trial, five patients between 30 60 years with diabetic wounds were enrolled. To cover wounds, acellular amniotic membrane mesenchymal (WJSCs) was used for 9 days, every 3 days follow‐up 1 month. The percentage time size recorded each patient. Results treated patients, significantly decreased, after 6 declined ( P < 0.002). Conclusion As WJSCs could accelerate they can be an alternative source tissue engineering repair