Treatment of total pelvic organ prolapse using a whole biological patch: A pilot study of 17 patients

• DOI: 10.1111/jog.13155
• Publication Date: 2016-10-20T09:22:51Z
• Authors: Xianghua Liang; Lili Zhang; Yanwei Lv
• Keywords: Uterosacral ligament; Hymen

Abstract Aim A complete and non‐splice porcine small‐intestine submucosa (SIS) patch was used for total pelvic anatomical repair of organ prolapse. Methods This study included a 17 patients with severe prolapse, including five combined stress urinary incontinence (SUI). Panhysterectomy performed, then SIS placed on the anterior (posterior) vaginal wall. The top wall moved to corresponding side wall, sutured bilateral uterosacral ligaments, sacrospinous ligament, arcus tendineus fasciae pelvis. SUI addressed at same time. ‘Failure’ defined as or posterior prolapse beyond hymen. Results mean follow‐up duration 11.6 ± 7.45 months (2–24 months). No symptom recurrence observed in SUI. One patient who underwent placement experienced stage II after surgery. fornix remaining patches were restored stable positions (92.85%). damage, infection, erosion, rejection observed, no blood transfusion necessary. Conclusion is first implement using SIS. Our results suggest that this new surgical method safe can achieve satisfactory therapeutic effects, especially