High‐grade vaginal intraepithelial neoplasia after hysterectomy for high‐grade cervical intraepithelial neoplasia: Is hysterectomy a “definitive” treatment compared to conization?

• DOI: 10.1111/jog.15723
• Publication Date: 2023-06-25T01:46:11Z
• Authors: Miyu Tanaka; Koji Yamanoi; Mana Taki; Sachiko Kitamura; Masumi Sunada; Yoshitsugu Chigusa; Akihito Horie; Ken Yamaguchi; Junzo Hamanishi; Masaki Mandai
• Keywords: Cervical conization; Laparoscopic hysterectomy

We investigated the frequency of early recurrence vaginal intraepithelial neoplasia grade 2/3 (VaIN 2/3) (within 2 years) after hysterectomy for cervical 3 (CIN3). The characteristics clinicopathological factors common to them were explored including different surgical methods.As a retrospective observational study, total 647 CIN3 patients divided into conization and group (C group, n = 492; H 155), HSIL (CIN2/3 or VaIN2/3) within years surgery was evaluated. A stratified analyses performed. Surgical methods trans-abdominal, trans-vaginal, laparoscopic.The VaIN3 detected in four cases (2.6%) which similar that CIN2/3 C 12 out 491 (2.4%). who developed significantly older than those did not (median, VaIN3: 71.0; VaIN1 less: 48.0; p < 0.0001). All 5 months, although majority negative margin (3/4 cases; negative). method related recurrence.For whom is main treatment, can develop 2.6% very shortly operation even if negative. elder age, higher risk could be. Laparoscopic considered be acceptable hysterectomy.