The persistence of HPV type‐specific infections in patients following colposcopic examination: An observational study

• DOI: 10.1111/jog.16301
• Publication Date: 2025-04-24T04:11:27Z
• Authors: Serkan Akis; Canan Kabaca; Yunus Emre Purut; Esra Keles; Ugur Kemal Ozturk; Mine Guray Uzun; Murat Api
• Keywords: Endocervical curettage; Persistence (discontinuity)

Abstract Aim High‐risk HPV infection is a necessary but not sufficient factor for the development of precancerous lesions and cervical cancer. Beyond mere positivity, persistence over time plays crucial role. This study aims to evaluate clearance rates 16 18 genotypes. Methods The cytology results were reported using 2014 Bethesda System classification. samples analyzed Roche Cobas® 4800 tests. Patients with any genotype other than or 18, those missing data, who lost follow‐up, underwent excisional procedures hysterectomy, high‐grade dysplasia excluded from this study. Results Among 191 patients (mean age: 41.2 ± 0.6 years, 16.8% postmenopausal), mean follow‐up was 21.6 0.7 months. No significant differences found between groups in age, duration, biopsy, endocervical curettage results. However, had higher rate (28.2%), abnormal more frequent group ( p = 0.038). Conclusions Around 25% persistent infection. Close monitoring essential CIN 1 on initial colposcopy, as they may have risk progressing compared without dysplasia.