Nocturnal autonomic nervous system activity and morning proinflammatory cytokines in young adult African Americans

• DOI: 10.1111/jsr.12480
• Publication Date: 2017-02-17T05:02:38Z
• Authors: Kimberly A. Bell; Ihori Kobayashi; Yuanxiu Chen; Thomas A. Mellman
• Keywords: Proinflammatory cytokine

Summary Compromised sleep and increased sympathetic nervous system ( SNS ) activity are implicated in the pathogenesis of, disparities in, cardiovascular disease. Parasympathetic dominance during may be important for health. Sleep autonomic balance influence immune activity, which impacts atherogenesis. We evaluated relationships between morning levels of activating cytokines, C‐reactive protein CRP interleukin IL )‐6. Ninety‐four (59 female) young adult African Americans without medical conditions substance use disorders spent 2 consecutive nights a clinical research unit recordings blood drawing on awakening. Cardiac tracings from second recording were analysed heart rate variability HRV ). Body mass index was only non‐ measure correlated with cytokine levels. Indicators presleep, first non‐rapid eye movement REM periods independently ‐6 Altered modifiable factor that influences activation.