Decreasing prevalence and stagnating incidence of Hepatitis C‐co‐infection among a cohort of HIV‐1‐positive patients, with a majority of men who have sex with men, in Germany, 1996–2019

• DOI: 10.1111/jvh.13670
• Publication Date: 2022-03-18T13:39:11Z
• Authors: Amrei Krings; Daniel Schmidt; Karolin Meixenberger; Norbert Bannert; Dieter Münstermann; Carsten Tiemann; Christian Kollan; Barbara Gunsenhei...
• Keywords: Hepatitis C

Co-infection with Hepatitis C virus (HCV) among HIV-positive patients leads to accelerated progression of liver disease and AIDS. Due increased HCV prevalence incidence, co-infection requires monitoring trends individuals. This will help target prevention strategies support reach the global goals eliminating viral hepatitis as a public health threat. In this analysis incidence were determined for years 1996-2019 from yearly blood samples questionnaire details HIV-1-positive patients, majority men who have sex men, belonging nationwide, multicentre observational, prospective cohort study. The results show that acute/chronic resolved infection until 2014 12%. Since then, rapidly decreased infections showed steady increase. was highest in 2010 lowest 2017; however, no significant change could be seen over years. Therefore, introduction directly-acting antiviral agents treatment notably potentially infection. Nevertheless, these study participants remain high compared general population justify need continuous efforts